Glutathione & oxidative stress
Glutathione is the cell's main internal antioxidant; she explains that glycine plus cysteine (e.g., from NAC) can restore it, countering oxidative stress tied to cognitive decline, inflammation, heart disease, and insulin resistance.
12 interventions act here
Glycine
Amino acid that supports glutathione production with NAC and may deepen slow-wave sleep.
I've used it
Methylene Blue
Century-old dye and drug that shuttles electrons in mitochondria; low doses studied for Alzheimer's.
Watching
N-acetylcysteine (NAC)
Cysteine source that cells use to make glutathione, the antioxidant that declines with age.
I've used it
Plasmalogens
Membrane phospholipids that act as the brain's last-line antioxidant; levels are very low in Alzheimer's.
Watching
L-Glutamine
Abundant amino acid fueling gut lining cells and mucus; she takes it to protect the gut barrier.
In my stack
Light at Night & Melatonin
Bright days and dark nights maximize melatonin, an antioxidant linked to lower mortality and Alzheimer's protection.
I've used it
Resveratrol
Grape polyphenol in her stack, linked to heart health, lower inflammation, FOXO3/sirtuin activation, and fading age spots.
In my stack
Methionine & Sulfur Amino Acid Restriction
Limiting methionine and cysteine extends lifespan in animals and lowers IGF-1; intermittent versions may spare muscle.
Watching
Fisetin & Quercetin
Plant flavonoids studied as senolytics that clear senescent 'zombie' cells and dampen inflammatory signaling.
In my stack
GHK-Cu (copper peptide)
Copper-binding tripeptide that declines with age and supports skin, wound healing, hair and lung repair.
I've used it
Microplastics Reduction
Cutting nanoplastic exposure, found in arterial plaque and brain tissue, and keeping the gut barrier strong.
I've used it
Luteolin
Flavonoid from herbs and vegetables with anti-inflammatory, antihistamine, and possibly neuroprotective effects, mostly shown in cells and animals.
Watching