Applying science to increase healthspan
Kind of like pornography, we all know aging when we see it. There is a specific point when suddenly someone looks old. Like they have crossed some invisible threshold, moving from healthy and older into the twilight area at the …
Alpha-ketoglutarate is a key molecule produced in your cells. Recently, research studies have shown that it may play a key role in healthy aging, including increasing healthspan and lifespan. What is alpha-ketoglutarate? Alpha-ketoglutarate (αKG) is a molecule that cells produce. …
A recent study on sleep and dementia points out (once again) that sleep is essential for good health in aging. The study found that decreased sleep, such as 6 hours or less per night, during your 50s and 60s increases …
I read a lot of studies on health and genetics, and I keep finding research on the mineral lithium popping up. Topics such as circadian rhythm dysfunction, Alzheimer’s disease, telomere length, type 2 diabetes, and obesity… all linked back to …
TNF-alpha (tumor necrosis factor alpha) is a proinflammatory cytokine upregulated in aging. TNF-alpha acts as a signaling molecule in our immune system and is important in our innate immune response. But chronically elevated TNF-alpha is one cause of the diseases …
Cellular senescence is a natural process that stops the reproduction of cells. While senescence happens throughout life, in aging, an accumulation of excess senescent cells seems to be at the heart of many age-related diseases. What is cellular senescence? Senescence …
Luteolin is a flavonoid found in herbs and vegetables. Research shows that it has numerous anti-inflammatory and antimicrobial effects. Additionally, some research shows that luteolin may help to stop the proliferation of certain cancer cells. The goal here is to …
A decades-old diabetes drug now holds promise for increasing healthspan. Research shows that metformin may reduce the risk of some of the diseases of aging, thus increasing the number of years someone is healthy. What is metformin? Metformin, also known …
GHK-Cu is a tiny little peptide that can be absorbed transdermally. It is often advertised as a way to reduce skin aging. While there are some good studies on it as a ‘beauty’ product, that is just the tip of …
Have you ever wondered why you are much more likely to have a cold in the winter than in the summer? It turns out that researchers have puzzled over the seasonality of respiratory viruses for decades. In 1926, one scientist …
A recent study in the journal Nature explains the latest research on a fascinating peptide known as MOTS-c. A little background first: Small peptide molecules are made up of 2-50 amino acids. Amino acids also makeup protiens but in chains …
A recent study in Cell reported on experiments regarding mitochondrial function and amyloid protein accumulation in the muscles.[ref] The researchers used animal models and human muscle tissue to determine that amyloid-like protein deposits occur in muscle during aging. Amyloid proteins …
Calculators for predicting biological age: The idea of biological age is that it shows how your lifestyle and genetics interact to estimate your cellular age more accurately than what the calendar says (chronological age). These biological age calculators are based …
A 2013 paper in the journal Cell defines the way we think of aging as a disease. In the paper, the authors break down the process of aging into what they called the ‘Hallmarks of Aging’. It is essentially a …
There are several genes known as “longevity” genes. Specific variants of these genes have an association with an increased likelihood of living to be 100 or more. And…more importantly, these genetic variants have links to a longer ‘healthspan’. Longevity: The …