Gum Disease is Linked to Alzheimer’s

The link between gum disease, or periodontal disease, and dementia has been known for a while. One theory has been that increased inflammatory cytokines in the gums — chronic inflammation – caused the increased risk of dementia. A recent review …

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Taurine Deficiency in Aging

Will taurine supplements make you live longer? A new study in the journal Science points to taurine deficiency as a driving factor in aging. The study examined taurine levels in mice, monkeys and humans and found that levels declined with …

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Improving cognitive function with peppermint?

A recent animal study in Frontiers in Immunology showed intriguing results that tie together the olfactory system, immune system, cognitive function, and Alzheimer’s disease. First a little background… As odd as it may seem, both Alzheimer’s and Parkinson’s are related …

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Longevity and Genetic Trade Offs

Genetic variants, or polymorphisms, are the common changes that can affect gene function a little bit. These changes make us all unique – from traits like hair color or eye color to the things that ‘run in the family’, like …

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Stopping Inflammaging: SPMs to the rescue?

Inflammaging: What is it and how can you prevent it Inflammaging refers to low-grade, sterile, chronic inflammation that increases with age and can contribute to health declines, age-related diseases, and frailty. The exact causes are still unclear, but one theory …

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Alzheimer’s as an Autoimmune Disease

To me, the idea of living longer is only appealing without the prospect of age-related neurodegeneration. Healthspan is my goal, and the prevention of Alzheimer’s is a major focus. For decades, research on Alzheimer’s has focused on amyloid-beta plaques and …

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Spermidine and Healthspan

Spermidine is a biogenic amine with many potential anti-aging benefits, ranging from extending healthspan to improving vaccine efficacy in older adults. I’ll dig into the research on the topic, explore the clinical trials, and explain why increasing spermidine can sometimes …

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Targeting Cellular Senescence Due to Covid

New research on COVID-19 shows the important role of cellular senescence in the high mortality rates in the elderly. Elderly people are much more vulnerable to the flu, respiratory infections, and sepsis than middle-aged or younger adults. We all know …

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